血管病変に起因する脳実質内出血での、二次性脳出血のリスク評価に関する論文。
脳出血症例も多くコミットしていますが、この論文は知らなかったので、勉強しましたので、覚書程度に記載します。
Practical Scoring System for the Identification of Patients with Intracranial Hemorrhage at Highest Risk of Harboring an Underlying Vascular Etiology: The Secondary Intracerebral Hemorrhage Score
AJNR 2010, 31, 1653-1660
AVM、An、dural venous sinus thrombosis、AVF、vasculopathy、moyamoya
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NCCT categorization
high probability 2
indeterminate 1
low probability 0
Age
18-45y/o 2
46-70y/o 1
≧71y/o 0
Sex
F 1
M 0
Neither known HTN nor impaired coagulation
Yes 1
No 0
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*high probability NCCT:(1) or (2)
(1)enlarged vessels or calcifications along the margins of the ICH
(2)hyperattenuation within a dural venous sinus or cortical vein along the presumed venous drainage path of the ICH
*low probability NCCT:
neither (1) nor (2)
ICH is located in the basal ganglia, thalamus, or brain stem.
*indeterminate NCCT:dosen't meet criteria for a high- or low-probability NCCT.
*impaired coagulation:PT-INR>3、aPTT>80、PLT<50,000、antiplatelet therapy
血管病変が潜在する可能性は、
score 3点 → 18.5%
score 4点 → 39%
score 5点 → 84.2%
score 6点 → 100%
3点以上はDSAで原因精査し、再出血予防治療を検討するのがいいと。